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Efficacy of Amantadine for Controlling Postoperative Pain in Cats Undergoing Ovariohysterectomy

Efficacy of Amantadine for Controlling Postoperative Pain in Cats Undergoing Ovariohysterectomy
  • Preemptive oral administration of amantadine at a dose of 5 mg/kg was effective at controlling postoperative pain in cats undergoing ovariohysterectomy

This study aimed to evaluate the effect of the preemptive administration of amantadine on postoperative analgesia in cats undergoing ovariohysterectomy and its influence on the physiological parameters. Twenty healthy domestic cats scheduled to undergo ovariohysterectomy at the Santa Cruz State University, Ilhéus, were divided into two groups: the control group (Group C; n = 10) and the amantadine group (Group A; n = 10). The cats in Group C received placebo capsules 30 min before the standard anesthetic protocol, whereas those in Group A received 5 mg/kg of amantadine orally 30 min before the standard anesthetic protocol. Postoperative pain was ...

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