Effect of a specially formulated diet on progression of heart enlargement in dogs with degenerative mitral valve disease

Previous studies in dogs with degenerative mitral valve disease (DMVD) have identified altered myocardial energy metabolism and oxidation, which might contribute to cardiac hypertrophy. Diets rich in medium chain fatty acids and antioxidants are a potential means of treatment. The aim of this study was to evaluate a specially formulated diet in dogs with subclinical DMVD over 365 days. One hundred twenty-seven dogs with unmedicated subclinical DMVD were included. The study's primary composite outcome measure was the sum of percentage change in LAD and left ventricular internal dimension at end-diastole (LVIDd) at day 365. In the per protocol cohort, the outcome measure ...

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