Effect of thromboprophylaxis on recurrence of thromboembolism and survival in cats following cardiogenic thromboembolism

This study aimed to assess the impact of clopidogrel or rivaroxaban administration on the recurrence of arterial thromboembolism (ATE) in cats that have recovered from cardiogenic ATE. This multicenter prospective double-masked protocol enrolled 45 cats that had recovered from cardiogenic ATE and were randomized to receive either clopidogrel (18.75 mg/cat, PO; n = 19) or rivaroxaban (2.5 mg/cat, PO; 26) as sole anticoagulant therapy for up to 2 years after the initial ATE. Primary outcome measures included recurrent ATE or death from any cause. In addition to bimonthly internet-based surveys of animal quality of life, echocardiograms were performed by veterinary cardiologists ...

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