Troponin-I Concentration in Horses with Cardiac Abnormalities

Cardiac troponin-I (cTnI) is a highly sensitive and specific marker of myocardial injury detectable in plasma by immunoassay techniques. The authors hypothesized that horses with clinically apparent cardiac disease would have elevated plasma cTnI when compared to normal horse plasma concentrations, with cTnI concentrations measured using a human immunoassay that has been reported on sparingly in previous studies with horses. Inclusion criteria over a 3-year period required a diagnosis of cardiac disease accompanied by electrocardiographic (ECG) and cardiac ultrasound examinations (n = 23) in adult horses (≥2 years of age). A second group of normal adult ponies (n = 12) was ...

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