Acute myeloid leukemia with peripheral lymph node involvement in dogs

The median survival after initial diagnosis for dogs given chemotherapy was 72 days

Acute myeloid leukemia (AML) can infiltrate extramedullary tissues, such as the liver, spleen, and lymph nodes and can be difficult to differentiate from lymphoma in cytologic and histologic specimens. The objective of this study was to identify cytologic features that would support a diagnosis of AML in peripheral lymph node aspirates, for which the authors used the term extramedullary AML (eAML). Medical records of 23 dogs with a diagnosis of AML and archived lymph node aspirate smears from 2016 to 2024 were reviewed across 4 institutions. Inclusion criteria included ≥50% myeloid blasts plus differentiating myeloid cells in lymph node smears, ...

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MICHELE TUMBARELLO, Med Vet, PhD Clinical pathology 02 December 2024

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Acute myeloid leukemia with peripheral lymph node involvement in dogs

Scientific Publishing

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Acute myeloid leukemia with peripheral lymph node involvement in dogs

Scientific Publishing