T lymphocyte subsets in dogs with chronic inflammatory enteropathy

Dysregulated T lymphocyte response is thought to play a key role in chronic intestinal inflammation (CIE). This prospective case-control study aimed to evaluate the presence of changes in peripheral and intestinal T lymphocyte subsets and to describe potential immune and inflammatory biomarkers in dogs with CIE. The authors evaluating peripheral and intestinal T lymphocytes using flow cytometry and inflammatory markers obtained from complete blood cell counts. Sixteen healthy dogs and 26 dogs with CIE were included. Dogs with CIE had higher peripheral activated T helper (Th) lymphocytes (87/μL [18-273] CIE, 44/μL [16-162] healthy control (HC, P = .013) and regulatory T cells ...

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