Polyuria and polydipsia during a short course of corticosteroids therapy
There was no significant difference in USG changes between methylprednisolone and prednisone groups
Glucocorticoids are widely used to treat canine allergic disorders, but they frequently cause polyuria and polydipsia (PUPD). At equipotent dosages, oral methylprednisolone is believed to cause less PUPD than prednisolone.
The authors performed a pilot randomized, open, parallel trial with 22 dogs with nonseasonal Atopic Dermatitis (AD) receiving either prednisolone or methylprednisolone at equipotent dosages, once daily for 14 days during the first phase of a restriction-provocation dietary trial. Before and on days 3, 7, and 14 after starting the glucocorticoids, owners estimated water consumption for 24 h. On the same days and before the glucocorticoid was given, owners collected ...
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