Diagnostic findings of equine glandular gastric disease
Gastric lymphoplasmacytic inflammation is associated with duodenal lymphoplasmacytic inflammation
The objective of this study was to compare small intestinal inflammation with gastric inflammation in horses with and without equine gastric glandular disease (EGGD).
Horses underwent endoscopy and were scored for EGGD. After euthanasia, stomachs were collected and macroscopically evaluated. Normal pyloric mucosa, glandular lesions, and small intestinal (duodenum, mid-jejunum, and ileum) samples were collected and processed for microscopic examination. Cellular infiltrate was scored. Immunohistochemistry (CD3, CD20, and Iba-1) was performed on the ventral pylorus and small intestine of horses with mild to moderate lymphoplasmacytic infiltrate. A Spearman's correlation coefficient was used to evaluate the relationship of EGGD grade with gastric ...
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