Effects of enrofloxacin administration on the fecal microbiota of chinchillas

The gastrointestinal microbiota plays a vital role in the digestion of chinchillas. Antibiotics may exert negative effects on the gut microbiota, with relatively limited research conducted on chinchillas in this regard. The goal of this pilot study was to assess the effects of enrofloxacin via subcutaneous injection or oral administration on the fecal microbiota of chinchillas. In a prospective, randomized, blinded, before and after experiment, nine healthy adult chinchillas were randomly assigned to one of three groups receiving no treatment (n = 3), enrofloxacin injection administered subcutaneously (SC) at 10 mg/kg (q12h, for 5 days, n = 3) and enrofloxacin tablet ...

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