Evaluation of the influence of phenoxybenzamine pretreatment on intraoperative cardiovascular variables in dogs with pheochromocytoma

The aim of this study was to compare cardiovascular outcomes in dogs undergoing adrenalectomy for pheochromocytoma with and without phenoxybenzamine pretreatment. A total of 65 medical records from dogs at 5 veterinary hospitals were reviewed from January 2004 to December 2021. Records were evaluated for systolic, mean, and diastolic arterial pressures; numbers of hypertensive and hypotensive episodes; highest and lowest systolic arterial pressure differences; dose and duration of phenoxybenzamine; and presence of intraoperative arrhythmias. Phenoxybenzamine-pretreated dogs (Group PT, n = 33) and dogs not receiving phenoxybenzamine (Group N, n = 31) were compared. The Shapiro-Wilk test was used to test for ...

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