Immune parameters in peripheral blood of dogs with malignant mammary tumours

Early-stage malignancies may not result in any significant changes in leukocyte subpopulations

The main adaptive immune cells are T and B lymphocytes and they play key roles in the induction of immune responses against canine mammary tumours. Investigating these cell subpopulations may lead to more precise diagnosis of these malignancies. The percentages of CD3+, CD4+ and CD8+ T cells and of CD21+ B cells in the peripheral blood of bitches with malignant mammary tumours were compared with those in the blood of healthy animals. The phenotypic features of peripheral blood leukocytes were evaluated by flow cytometry. There was a significant difference in the mean percentages of CD3+ lymphocytes between healthy (66.7%) and metastatic dogs ...

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MICHELE TUMBARELLO, Med Vet, PhD Haematology 17 July 2024

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Immune parameters in peripheral blood of dogs with malignant mammary tumours

Scientific Publishing

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Immune parameters in peripheral blood of dogs with malignant mammary tumours

Scientific Publishing