The treatment of canine chronic cutaneous lupus erythematosus (CCLE) variants generally requires immunosuppression, which often results in potentially severe adverse effects. Janus kinase inhibitors, like oclacitinib, might be a valuable treatment option due to their rapid inhibition of the action of interferons known to be relevant in the pathogenesis of CCLE.The aim of this study was to report the efficacy and safety of oral oclacitinib for the treatment...

Glucocorticoids are widely used to treat canine allergic disorders, but they frequently cause polyuria and polydipsia (PUPD). At equipotent dosages, oral methylprednisolone is believed to cause less PUPD than prednisolone. The authors performed a pilot randomized, open, parallel trial with 22 dogs with nonseasonal Atopic Dermatitis (AD) receiving either prednisolone or methylprednisolone at equipotent dosages, once daily for 14 days during the first phase of a restrict...