Assessment of symmetric dimethylarginine in goats with urolithiasis

Symmetric dimethylarginine (SDMA), a sensitive biomarker for detecting renal injury, has not been characterized in goats. In male small ruminants, obstructive urolithiasis (OU) is the most common urinary tract disease. Serum SDMA has the potential to be utilized as a diagnostic tool in assessing renal function of goats with OU before undergoing surgery, thus helping guide client's and veterinarian's treatment decision. This study aimed to establish an SDMA reference interval (RI) in healthy adult goats and describe SDMA concentrations in goats with OU. The authors hypothesized that the SDMA RI in healthy adult goats will be similar to that of ...

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