Assessment of the urinary microbiota in cats with urethral obstruction

Urethral obstruction (UO) is a devastating, common, and recurrent manifestation of feline interstitial cystitis (FIC) in male cats. The authors 1) investigated the differences in the microbiota of healthy cats versus cats with UO; 2) compared the urinary microbiota with the oral, preputial, and rectal microbiota; and 3) studied 16S rRNA gene sequencing to characterize the urinary microbiota. Cats with UO and age-matched healthy cats were prospectively included from July 2020 through April 2021. Exclusion criteria were evidence of urinary tract infection, urolithiasis, antimicrobial administration, urinary catheterization in the past 30 days, or a comorbidity. Both groups had a baseline CBC, ...

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