Urine anion gap evaluation in cats with chronic kidney disease

Ammonium excretion decreases as kidney function decreases in several species, including cats, and may have predictive or prognostic value in patients with chronic kidney disease (CKD). Urine ammonia measurement is not readily available in clinical practice, and urine anion gap (UAG) has been proposed as a surrogate test. The primary aim of this study was to evaluate the correlation between urine ammonia-to-creatinine ratio (UACR) and UAG in healthy cats and those with CKD; a second objective was to determine if a significant difference exists between UAG of healthy cats and cats with CKD. Urine samples were collected by cystocentesis from healthy ...

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