Wednesday, 07 December 2022
Causes of digestive disorders in beef cattle production systems
Written by Michele Tumbarello Med Vet PhD student- Ruminal acidosis occurred when there was high intake of starch-rich concentrate
The physicochemical characteristics of diets and faeces were evaluated in combination with data of rumen fluid and blood lactate collected from two distinct feedlot systems in Brazil to understand the causes and correlations to digestive disorders in these production systems. The data were collected during two visits to a finishing system which fed about 80,000 head per year, and four visits to two properties that fed 150 to 180 straight bred Nellore ...
Wednesday, 07 December 2022
Serum and urine biomarkers in cats with interstitial and bacterial cystitis
Written by Michele Tumbarello Med Vet PhD student- Serum NGF is a candidate biomarker that could be used in the diagnosis of FIC
Although feline urine is increasingly submitted for bacterial culture and susceptibility testing in veterinary practice, bacterial cystitis (BC) is relatively uncommon compared with feline interstitial cystitis (FIC), which shares similar clinical manifestations. Therefore, an investigation of certain urothelial (glycosaminoglycan [GAG], tissue inhibition metalloproteinase-2 [TIMP-2]), cytokine (interleukin 12 [IL-12]), and neurotrophic factor (nerve growth factor [NGF]) markers ...
Wednesday, 07 December 2022
Expression profile of immunoregulatory molecules in canine tumors
Written by Michele Tumbarello Med Vet PhD student- LGALS9 and CD48, were expressed in most canine tumors
Cancers utilize a variety of molecules to escape host immune responses. Better understanding the immune environment surrounding cancer may facilitate application of innovative cancer immunotherapies, such as immune checkpoint inhibitors, to dogs as well as humans. In this study, the authors screened the expression of 20 immune regulatory molecules in diverse canine tumors (n = 59). ...
Wednesday, 30 November 2022
Clinical Scoring Systems in the Newborn Calf
Written by Antonio Maria Tardo Med Vet PhD Student- To evaluate the clinical scores designed or adapted to bovine medicine that aim to assess newborn calf viability
A scoring system is an instrument that enables the scorers, including farmers, technicians, and veterinarians, to adopt a systematic approach for diagnosis or monitoring, as it decreases bias and confounding and increases objectivity. Practically, it is a number assigned to a patient that correlates with a probability that a diagnosis can be confirmed or that a specific outcome will follow. This article examines...
Wednesday, 30 November 2022
Primary immune-mediated polyarthritis in dogs
Written by Antonio Maria Tardo Med Vet PhD Student- Relapse of clinical signs was reported in 53% of dogs
The Objectives of this study was to provide a description of primary idiopathic immune-mediated polyarthritis, including long-term outcome and relapse rates, for dogs starting treatment with corticosteroids alone or corticosteroids with a second immunosuppressant.Medical records were reviewed between January 2012 and December 2017 to identify dogs diagnosed with primary immune-mediated polyarthritis. Data includ...
Wednesday, 30 November 2022
Transient myocardial thickening in two Toxoplasma gondii-positive cats
Written by Antonio Maria Tardo Med Vet PhD Student- Both cats received appropriate antiprotozoal and cardiovascular therapy
In this report, the authors provide detailed clinical, laboratory, electrocardiographic and echocardiographic descriptions of two Toxoplasma gondii-positive cats diagnosed with transient myocardial thickening (TMT) and acute myocardial injury (MI). In both cases, aetiological diagnosis was based on the antibody screening test (all cats had IgM titres ⩾1:64) and MI was demonstrated by a concomitant severe increase of the serum concentratio...
Friday, 25 November 2022
Hematology and plasma biochemistry reference values of juvenile undulate rays
Written by Antonio Maria Tardo Med Vet PhD Student- Blood samples from 43 undulate rays were analyzed for hematology and plasma biochemistry
Despite the paucity of published literature on elasmobranch hematology and biochemistry, great interspecific diversity has been observed.Blood samples from 43 undulate rays (Raja undulata) (23 males, 20 females) hatched and raised at Oceanogràfic Aquarium, were analyzed for hematology and plasma biochemistry. Animals were divided into two age groups: 1 yr old (28 skates) and 2 yr old (15 skates). Al...
Friday, 25 November 2022
Use of urinalysis during baseline diagnostics in dogs and cats
Written by Antonio Maria Tardo Med Vet PhD Student- Participants performed urinalyses much less frequently than blood work during a routine examination
The aim of this study was to describe how veterinarians utilise and perform urinalyses for dogs and cats.A survey, developed and distributed through the Veterinary Information Network, enlisted veterinarians who perform urinalyses for dogs and cats. Participants were directed to question banks based on whether urinalyses were performed in-house, by an outside diagnostic laboratory, or using an in-house automated instrument. Participants using mult...
Friday, 25 November 2022
Clinical and magnetic resonance imaging features of spinal lymphoma in cats
Written by Antonio Maria Tardo Med Vet PhD Student- The most frequent neurological signs were rapidly progressive paraparesis or paraplegia
This multicentric retrospective study describes the clinical and MRI features and pathological studies of spinal lymphoma in 27 cats. MRI characteristics and their possible correlations with histopathological findings were studied.The most frequent neurological signs were rapidly progressive paraparesis (62.9%) or paraplegia (22.2%). Bimodal age distribution was found with 40.7% of cats aged ≤2.5 years (63.6% of them FeLV positive), and 44.4% of cats aged ≥8...
Monday, 21 November 2022
Acute Phase Biomarkers in Racing Endurance Horses
Written by Antonio Maria Tardo Med Vet PhD Student- Endurance racing induces acute phase response in horses
This study aimed to evaluate if exercise-induced acute phase response (APR) occurs in endurance horses in response to the race.The study included 23 horses competing in an endurance competition with a successfully passed clinical examination before the race. Blood samples were collected before the start and within 30 min after the end of the race. Haematological and biochemical tests were performed and correlated to acute ph... More...
Monday, 21 November 2022
Canine and feline P-glycoprotein deficiency
Written by Antonio Maria Tardo Med Vet PhD Student- The so-called "ivermectin sensitivity" was determined to be a P-glycoprotein deficiency caused by a genetic variant of the MDR1
In 2001 the molecular genetic basis of so-called "ivermectin sensitivity" in herding breed dogs was determined to be a P-glycoprotein deficiency caused by a genetic variant of the MDR1 (ABCB1) gene often called "the MDR1 mutation." We have learned a great deal about P-glycoprotein's role in drug disposition since that discovery, namely that P-glycoprotein transports many more drugs than just macrocyclic lactones that P-glycoprotein mediated drug transport i...
Monday, 21 November 2022
Smartwatches exhibit high accuracy in evaluating heart rate and peripheral oxygen saturation in cats
Written by Antonio Maria Tardo Med Vet PhD Student- GF5xp and AppW6 exhibited high accuracy in evaluating HR and SpO2 in cats
The aim of this study was to evaluate the accuracy for 2 smartwatches with oximetry technology and optical wrist heart rate (HR) or single-lead Electrocardiography (ECG) technology (Fenix 5X Plus [GF5xp], Garmin Ltd and Apple Watch 6 [AppW6], Apple Inc, respectively) versus reference methods (ECG and transmittance pulse oximetry [TPO], respectively) in measuring HR and peripheral oxygen saturation of hemoglobin (SpO2) in cats.10 male client-owned cats aged 8 to 12 months a...
Wednesday, 16 November 2022
Diagnosis, Treatment and Prognosis of Canine Insulinoma
Written by Antonio Maria Tardo Med Vet PhD Student- The diagnosis of an insulinoma requires the demonstration of the simultaneous occurrence of hypoglycaemia and blood insulin levels that are normal or high
The most common pancreatic tumour in dogs is the insulinoma. Canine insulinomas are considered to be malignant in more than 95% of the cases because they almost always tend to metastasise. The diagnosis of an insulinoma requires the demonstration of the simultaneous occurrence of hypoglycaemia and blood insulin levels that are within or above the high end of the reference interval. The stagin...
Wednesday, 16 November 2022
Ultrasonographic diagnosis bovine respiratory disease in Holstein calves
Written by Antonio Maria Tardo Med Vet PhD Student- Thoracic ultrasound can be a reliable tool in the early BRD diagnosis of subclinical cases
Bovine respiratory disease (BRD) is the main cause of death in calves, and early BRD diagnosis saves lives. This study aimed to diagnose clinical and subclinical BRD in calves by assessing some biochemical alterations and ultrasonography (USG).Fifty-four Holstein dairy calves in Al-Sharqiyah Province, Egypt, were used in the study. They were divided into three groups. The first control group consisted of 10 clinically healthy calves. The second group consi... 
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