Treatment of Different Solid Tumours in Dogs

Chlorambucil is used in veterinary medicine for various cancers, while Toceranib, which was licenced for treating canine mast cell tumours, is now used against other solid tumours. Both drugs are generally safe, but their combined use has not been studied. This study aimed to investigate retrospectively the safety profile of the Chlorambucil-Toceranib combination against canine solid tumours. Medical records of dogs from two referral hospitals, treated with the combination of Chlorambucil and Toceranib from January 2020 to September 2024 were retrospectively evaluated. Thirty-eight dogs received this combination. Chlorambucil was administered at a median dose intensity of 15.1 mg/m2 per week, while ...

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