Pharmacology

Comparative pharmacokinetic evaluation of metronidazole in sheep and goats

22 January 2025Pharmacology

The bioavailability was relatively high in both animal species

Metronidazole (MTZ) is a 5-nitroimidazole compound recognized for its dual anti-bacterial and anti-protozoal properties. Non-approved in many countries for farm medicine, due to a lack of data in the literature, the stud...

Comparison of apixaban and rivaroxaban in dogs

22 November 2024Pharmacology

Weaning of these drugs in clinical patients might not be necessary

The comparative pharmacokinetics and pharmacodynamics (PK/PD) of apixaban and rivaroxaban after repeated administration have not been studied in dogs. This information will be critical to inform the development of effect...

Pharmacodynamics of 2 dosages of esomeprazole in dogs

20 November 2024Pharmacology

33% of dogs required q12h dosing to reach pH goals

Esomeprazole use is increasing in dogs, but the gastrointestinal adverse events associated with q12h dosing necessitate pharmacodynamic evaluation of a reduced dose and frequency of administration. This study aimed to co...

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Pharmacology

Comparative pharmacokinetic evaluation of metronidazole in sheep and goats

Comparison of apixaban and rivaroxaban in dogs

Pharmacodynamics of 2 dosages of esomeprazole in dogs

Scientific Publishing

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Pharmacology

Comparative pharmacokinetic evaluation of metronidazole in sheep and goats

Comparison of apixaban and rivaroxaban in dogs

Pharmacodynamics of 2 dosages of esomeprazole in dogs

Scientific Publishing