Clinical Use and Pharmacokinetics of gabapentin in Dogs, Cats, and Horses

This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, cats, and horses

Gabapentin is an anticonvulsant drug, which presents an established clinical efficacy in human patients for the management of refractory partial seizures, secondarily generalized tonic-clonic seizures, and for the control of chronic neuropathic pain. Gabapentin was synthesized as a structural analogue of the inhibitory neurotransmitter GABA, with GABA-mimetic effects, able to cross the blood-brain barrier. In veterinary medicine, is extra-label used in combination with other treatments to control seizures when other drugs are no longer effective or become toxic or for neuropathic pain treatment and anxiety. This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, ...

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Antonio Maria Tardo Med Vet PhD Pharmacology 03 July 2023

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Clinical Use and Pharmacokinetics of gabapentin in Dogs, Cats, and Horses

Scientific Publishing

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Clinical Use and Pharmacokinetics of gabapentin in Dogs, Cats, and Horses

Scientific Publishing