Regulatory T lymphocytes and selected cytokines in equine asthma

Horses with severe equine asthma had higher concentrations of MMP-9 in the BALF

This study determined Tregs and inflammatory cytokines in BALF and peripheral blood (PB) of adult horses with mild and severe asthma and different BALF cytological inflammation profiles. Horses of diverse breeds with asthma (age range: 2-20 years, n = 24) were divided into groups according to the number of points obtained in a standardized clinical scoring system (mild-moderate equine asthma - MEA, severe equine asthma - SEA) and according to the inflammation type based on cytological finding. Plasma levels of IFN-γ, IL-4, IL-10, IL-17 and MMP-9 in the BALF were determined by ELISA. Tregs in the BALF and PB were detected ...

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Antonio Maria Tardo Med Vet PhD Pneumology 04 September 2023

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Regulatory T lymphocytes and selected cytokines in equine asthma

Scientific Publishing

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Regulatory T lymphocytes and selected cytokines in equine asthma

Scientific Publishing